MTN8 winners, Orlando Pirates have a shot at another trophy if they are victorious over bottom of the log Maritzburg United this weekend.
The Nedbank Cup Round of 16 match sees the Team of Choice come fresh off a two week break, while the Bucs go into the tie after a jam-packed fixture schedule, competing in three games in 10 days.
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Though the Sea Robbers will not go into the game lightly, with a quarter-final spot at stake, Maritzburg will likely rely on their top performers if they plan to deny Pirates the chance at a second potential title.
After only winning one match in six games in all competitions, the Team of Choice could cause an upset, if two key players are in top form.
Thabiso Kutumela and Judas Moseamedi:
Central to Maritzburg's attack is Moseamedi, who regularly threads passes to Kutumela. The duo has contributed to eight goals during this campaign.
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Pirates have injury concerns, with Tshegofatso Mabasa, Abel Mabaso, Thembinkosi Lorch and Gabadinho Mhango injured, the Bucs will rely on two influential attackers.
Vincent Pule and Fortune Makaringe:
Pule will most likely come in upfront to replace the injured Mhango and Makaringe in midfield will prove to be penetrative for the Bucs. Pule's creativity and ability to feed Makaringe could be pivotal to the Soweto giants advancing in this round.
The crunch clash is scheduled for Saturday at 18:00 at the at Harry Gwala Stadium.