Wolverhampton Wanderers will head to the second leg with the advantage in their last 16 tie after registering a 1-1 draw at Olympiakos.
Despite having Ruben Semedo sent off in the 28th minute, the hosts got the opening goal through Youssef El-Arabi, who netted the away goal at Arsenal, after 54 minutes.
However, Wolves managed to get back in the contest thanks to second-half substitute Pedro Neto, who secured the away goal in the 67th minute.
FC Basel are on the brink of qualifying for the quarter-finals after 3-0 win away to Eintracht Frankfurt.
Samuele Campo got the Swiss outfit up and running in the 27th minute, before Kevin Bua and Fabian Frei completed the scoring in the second half.
Istanbul Basaksehir have taken a slight advantage in their last 16 tie after edging FC Copenhagen 1-0 in Istanbul, with Edin Visca netting the game's only goal from the penalty spot.
Steven Gerrard's Rangers are on the brink waving goodbye to European football after a 3-1 loss to Bayer Leverkusen at Ibrox Stadium.
Kai Havertz, Charles Aranguiz and Leon Bailey got the away goals for Leverkusen while George Edmundson bagged Rangers' consolation.
Shakhtar Donetsk have put themselves in a good position to qualify for the last eight after defeating Wolfsburg in Germany.
Junior Moraes and Marcos Antonio netted in the first and second half respectively for the Ukraine outfit, although Jon Brooks netted on 48 minutes to give Wolfsburg a glimmer of hope.