West Ham United continued their winning start in Group H after defeating KRC Genk on Thursday evening.
Craig Dawson put the Hammers ahead on the stroke of halftime, while Issa Diop and Jarrod Bowen added the second and third goals just before the hour mark.
Napoli got their group stage campaign up and running with a 2-0 triumph over Legia Warsaw.
After a scoreless first half, Lorenzo Insigne, Victor Osimhen and Matteo Politano got the goals for the Naples outfit in the final 15 minutes.
AS Monaco got back to winning ways after defeating PSV Eindhoven 2-1 at the Philps Stadion.
Myron Moadu gave the French side the early lead after opening the scoring in the 19th minute, before Cody Gakpo got PSV level on 59 minutes.
With the game seemingly headed for a draw, Sofiane Diop popped up with the winning goal in the 89th minute for the French side.
Steven Gerrard's Rangers finally got off the mark in the group stages with a 2-0 victory over Brondby.
Rangers got their first win in Group A after defeating Danish outfit Brondby 2-0 at the Ibrox Stadium.
The Scottish champions went in front through Leon Balogun's strike in the 18th minute before Kemar Roofe doubled the advantage on 30 minutes.
Fenerbahce remain without a win in Group D after drawing 2-2 with Royal Antwerp on Thursday evening.
Enner Valencia bagged a brace to put the hosts 2-1 up after Mbwana Samatta opened the scoring for Antwerp, before Peter Gerkens bagged the equaliser in the 62nd minute.